Majeed Haris,  Sussman Marshall,  Feldman Brian,  Man Carina,  Blanchette Victor,  Doria Andrea

Final Pr. ID: Poster #: SCI-051

To evaluate the T2 map relaxation times in healthy male children and adolescent ankle cartilage under altered magnetic resonance image (MRI) protocols and to document trends in these T2 relaxation times with varying ages and body mass index (BMI). Read More

Authors:  Majeed Haris , Sussman Marshall , Feldman Brian , Man Carina , Blanchette Victor , Doria Andrea

Keywords:  Hemophilia, Optimization Protocol, T2 Map MRI

Tan Timothy Shao Ern,  Teo Eu Leong Harvey James

Final Pr. ID: Poster #: EDU-065

Hemophilia is an inherited bleeding disorder occurring mainly in males. Bleeding in these patients may occur acutely in different and unusual locations throughout the body, sometimes with life-threatening consequences. Repeated bleeding episodes may cause chronic manifestations, frequently resulting in severe morbidity to the patient.

The most common manifestation of the disease is acute hemorrhage into joints causing hemarthrosis. This usually affects large joints such as the knee, elbow, ankle, hip and shoulder. Repeated episodes can lead to pannus formation with destruction of the synovium, cartilage and subchondral bone resulting in a condition known as hemophilic arthropathy. In the long term, this may result in debilitating chronic pain and contractures.

Soft tissue hematomas are another frequent manifestation of the disease. Chronic, organized hematomas are also known as hemophilic pseudotumours. These lesions may become calcified or infected and may result in bone erosion with pathological fractures.

Bleeding may occur in other parts of the body such as the brain and spine causing acute stroke with subsequent seizures and neurological deficits. Intra-abdominal bleeding into the abdominal cavities and intramural bleeding into the genitourinary or gastrointestinal walls may rarely occur. It is hence important for radiologists and clinicians to recognize these complications in order to detect and treat these conditions in a timely manner.

The aim of this exhibit is to familiarize readers with the imaging features of acute and chronic bleeding complications in hemophilia patients, highlighting unusual locations in the body where these can occur, using multimodality imaging i.e. Plain radiographs, ultrasound, CT and MRI. Read More

Authors:  Tan Timothy Shao Ern , Teo Eu Leong Harvey James

Keywords:  Hemophilia, Bleeding, Hemarthrosis

Panwar Jyoti,  Negrao Jose,  Fernandes Artur,  Antunes Sandra,  Dertkigil Sergio,  Sakuma Emerson,  Ozelo Margareth,  Zhang Ningning,  Huo Aihua,  Peng Yun,  Wu Runhui,  Tolend Mirkamal,  Zhou Fang,  Li Yingjia,  Sun Jing,  Zhou Alex,  Mohanta Arun,  Jarrin Jose,  Panwar Sanuj,  Luke Koon Hung,  Blanchette Victor,  Doria Andrea,  Daruge Paulo,  Bordalo Rodrigues Marcelo,  Carneiro Jorge,  D’amico Elbio,  Villaça Paula,  De Ávila Fernandes Eloy,  De Aguiar Vilela Mitraud Sonia

Final Pr. ID: Poster #: SCI-022

Optimization of ultrasound (US) scanning planes for evaluation of different joint components of subjects with blood-induced arthropathy can decrease scanning time without compromising diagnostic information. The purpose of this study was to identify the most diagnostically informative set of US planes for assessment of arthropathy in growing joints of persons with hemophilia based on frequency of findings. Read More

Authors:  Panwar Jyoti , Negrao Jose , Fernandes Artur , Antunes Sandra , Dertkigil Sergio , Sakuma Emerson , Ozelo Margareth , Zhang Ningning , Huo Aihua , Peng Yun , Wu Runhui , Tolend Mirkamal , Zhou Fang , Li Yingjia , Sun Jing , Zhou Alex , Mohanta Arun , Jarrin Jose , Panwar Sanuj , Luke Koon Hung , Blanchette Victor , Doria Andrea , Daruge Paulo , Bordalo Rodrigues Marcelo , Carneiro Jorge , D’amico Elbio , Villaça Paula , De Ávila Fernandes Eloy , De Aguiar Vilela Mitraud Sonia

Keywords:  Hemophilia, Ultrasound, Protocol

Bandarkar Anjum,  Cielma Tara,  Holley Danyelle,  Adeyiga Adebunmi

Final Pr. ID: Poster #: EDU-042

Background: Hemophilia is a rare X-linked recessive bleeding disorder characterized by the absence of one of the coagulation factors including factor VIII in hemophilia A and factor IX in hemophilia B. Amongst the complications, muscle hemorrhage is the second most common type of hemorrhage in hemophilia, second only to hemarthrosis. Bleeding may be precipitated by trauma or fractures or may be spontaneous. Hemorrhage into the large muscle groups of the upper and lower extremities, can cause tissue compartment syndrome, nerve compression, and potential tissue death. A child with hemophilia and muscle hemorrhage may present with focal swelling, pain, or refusal to use the affected body part. Early recognition and treatment of muscle hemorrhages can prevent compartment syndrome and longterm complications, reduce pain, and allow a quick return to normal function and activity.
Aims:
1. To describe utility of rapid ultrasound in detecting muscle hemorrhages in children with hemophilia.

2. To illustrate sonographic appearances of muscle hemorrhages in various locations in the body. Read More

Authors:  Bandarkar Anjum , Cielma Tara , Holley Danyelle , Adeyiga Adebunmi

Keywords:  Hemophilia, Muscle hemorrhage, Hematoma

Ahmed Humayun,  Wang Kuan Chung,  Sussman Marshall,  Amirabadi Afsaneh,  Moineddin Rahim,  Wells Greg,  Man Carina,  Blanchette Victor,  Doria Andrea

Final Pr. ID: Poster #: SCI-036

1. To determine short-term interval changes in T2 maps of knee cartilage of healthy boys before and after a 2-minute knee-squat exercise at 1.5T and 3T MRI; 2. To determine interval changes in T2 maps pre-exercise at 1.5T vs. 3T, and post-exercise at 1.5T vs. 3T; 3. To determine interval changes pre- and post-exercise among minimal-, moderate-, and high-activity subjects at 1.5T and 3T; and 4. To determine inter- and intra-reader reliability of 1.5 and 3T values. Read More

Authors:  Ahmed Humayun , Wang Kuan Chung , Sussman Marshall , Amirabadi Afsaneh , Moineddin Rahim , Wells Greg , Man Carina , Blanchette Victor , Doria Andrea

Keywords:  Hemophilia, Arthropathy, Pediatrics, Inherited bleeding disorders, T2 mapping MRI