Final Pr. ID: Poster #: EDU-071
Chronic cerebrovascular disease is common in pediatric sickle cell patients, and these children often require serial imaging to assess cerebral blood flow perfusion. ASL MRI has been shown to be an effective technique to assess cerebral blood flow, but the evaluation of perfusion reserve is also of value to ordering clinicians. This educational exhibit describes the use of the vasodilator acetazolamide to gauge potential changes in perfusion as determined by ASL MRI. The biochemical basis for cerebrovascular autoregulation and mechanism of acetazolamide are discussed. Read More
Authors: Pfeifer Cory , Miller Jeffrey
Keywords: arterial spin labeling MRI, cerebral blood perfusion, acetazolamide
Didier Ryne, Martin-saavedra Juan, Sridharan Anush, Larson Abby, Coons Barbara, Coleman Beverly, Davey Marcus, Hedrick Holly, Flake Alan
Final Pr. ID: Paper #: 118
Assessment of fetal brain perfusion with contrast-enhanced ultrasound (CEUS) has not been performed in vivo in congenital diaphragmatic hernia (CDH). The development of the EXTra-uterine Environment for Neonatal Development allows investigation of CEUS and fetal brain perfusion parameters. The purpose of this study was to assess for aberrations in brain perfusion using CEUS in fetal lambs with CDH and correlate with cardiac output data. Read More
Authors: Didier Ryne , Martin-saavedra Juan , Sridharan Anush , Larson Abby , Coons Barbara , Coleman Beverly , Davey Marcus , Hedrick Holly , Flake Alan
Keywords: Congenital Diaphragmatic Hernia, Brain Perfusion, Contrast Enhanced Ultrasound
Rapp Jordan, Saul David, Kaplan Summer, Barrera Christian, Otero Hansel
Final Pr. ID: Poster #: EDU-099
Background: Dual source dual-energy CT scanners (DECT) has allowed for the collection of two data sets with a single scan, opening the potential for functional data acquisition. The technique combines two energy beams at distinct voltages applied concurrently during a single scanning phase. The source data can be combined to generate a single mixed composite image, or iodine can be subtracted to create a contrast map or a virtual non-contrast image. The result is functional information in the setting of decreased radiation dose when replacing a biphasic scan, or dose neutral when compared to conventional single source CT. Post processing lung perfusion software allows for imaging display (qualification) and quantification of iodinated contrast volumes in the lungs, a surrogate for lung perfusion.
Purpose:
This educational exhibit will demonstrate: 1. How to perform DECT in children, 2. How to use postprocessing software, and 3. How to interpret lung perfusion results through clinical examples of current pediatric clinical indications including pulmonary embolism, lung hypoplasia, pulmonary AV malformation, and pulmonary hypertension.
Conclusion:
Through this exhibit, readers will gain familiarity with technical aspects of DECT of the lungs in children, understand the basics of post processing and recognize focal or regional perfusion defects, segmented perfusion analysis, and focal lesion perfusion characteristics as well as identify future applications.
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Authors: Rapp Jordan , Saul David , Kaplan Summer , Barrera Christian , Otero Hansel
Keywords: dual energy, thoracic, perfusion
Aldraihem Ahmed, Abdeen Nishard
Final Pr. ID: Poster #: SCI-047
To determine the inter-observer agreement in measurement of relative cerebral blood volume (rCBV) in pediatric brain tumors, using normal grey matter as a control. Read More
Authors: Aldraihem Ahmed , Abdeen Nishard
Keywords: brain tumor, T2* perfusion, interobserver agreement
Mcgovern Jonathan, Zuccoli Giulio, Goyal Rakesh
Final Pr. ID: Poster #: CR-063
To evaluate multimodal magnetic resonance imaging (MRI) characteristics in pediatric patients diagnosed with posterior reversible encephalopathy syndrome (PRES). Read More
Authors: Mcgovern Jonathan , Zuccoli Giulio , Goyal Rakesh
Cardenas Agustin, Murnick Jonathan, Whitehead Matthew
Final Pr. ID: Poster #: EDU-007
Recent literature has illuminated increasing diagnostic uses of arterial spin labeling (ASL). This MR technique obtains accurate and reliable CBF measurements non-invasively and can be performed multiple times during the same exam, unlike other perfusion techniques.
A wide variety of entities, including normal variants, pathological conditions, and technical errors can demonstrate abnormal CBF values.
This Educational Exhibit has three main purposes:
1. To classify the main abnormal ASL perfusion patterns in the pediatric brain.
2. To discuss the potential clinical significance of abnormal ASL values.
3. To discuss the utility of this technique in the pediatric clinical setting.
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Authors: Cardenas Agustin , Murnick Jonathan , Whitehead Matthew
Keywords: ASL, arterial spin labeling, perfusion
Patel Hanisha, Mayl Jonathan, Maheshwari Mohit, Mohan Suyash, Chandra Tushar
Final Pr. ID: Poster #: EDU-055
Moyamoya disease (MMD) is an uncommon cerebrovascular disease that is characterized by progressive stenosis of the terminal portion of the internal carotid artery and its main branches, which is accompanied by the development of collateral vessels at the base of the brain. The purpose of this educational exhibit is to provide a succinct review of the imaging findings of MMD and its frequently associated complications, demonstrate the role of various imaging techniques in diagnosis and clinical decision making, and give an overview of surgical approaches and post operative appearances. Read More
Authors: Patel Hanisha , Mayl Jonathan , Maheshwari Mohit , Mohan Suyash , Chandra Tushar
Keywords: Moyamoya, MR Angiogram, MR perfusion