Lymphoma is the third most frequent pediatric cancer after leukemia and brain tumors and can involve different organs with multiple imaging presentations and characteristics. Given that, pediatric radiologists must be familiar with the different imaging patterns that this disease represents in order to come up with the proper diagnosis at every moment. However, sometimes lymphoma imaging presentation can be challenging and simulate other diseases (historically called the great mimicker), which can mislead us to make a wrong diagnosis with consequent inappropriate or delayed treatment. On account of that, we have selected several cases throughout different years presenting at two institutions with imaging presentations resembling pediatric lymphoma, some of them resulting in true lymphoproliferative processes and others turning out to be simulating pathologies. We display the different cases on this educational poster and show what are the clues (if present) to properly distinguish between lymphomatous and simulating diseases from the imaging point of view and always with clinical correlation. In summary, the main purpose of this poster is to represent the imaging differences between pediatric lymphoma and its possible mimickers through the presentation of different teaching cases and to highlight the clues that can help pediatric radiologists to distinguish adequately the different diseases. Read More
Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024
Authors: Arenos-abril Jesus, Gonzalo Marta, Coblenzt Ailish
Background: Li-Fraumeni Syndrome (LFS) is an autosomal dominant disorder that predisposes individuals to cancer, associated with mutations in the P53 gene. The most common tumors associated with LFS include breast cancer, osteosarcomas and other sarcomas. Less frequent but also seen are brain tumors, adrenocortical carcinomas and leukemia. However, tumors can manifest almost anywhere in the body. Given the increased cancer risk, close surveillance is imperative for early cancer detection; guidelines recommend annual Whole Body MRI (WB-MRI) surveillance, along with a series of other imaging and laboratory studies. WB-MRI protocols vary across centers. Although the short tau inversion recovery (STIR)/T2-weighted sequence is accurate for early cancer detection, the combination of STIR/T2 and diffusion-weighted (DW) sequences further increases the diagnostic accuracy of MRI, but at the cost of increased scan time. Teaching Points: In this educational poster, we will show pediatric surveillance MRI scans in patients with LFS where the utilization of DW-MRI was essential for the diagnosis of cancer or associated conditions, not identified by STIR/T2-weighted MRI solely, along with WB-MRI protocols used in different centers with corresponding total scan time. Our objective is to demonstrate the added value of using DWI in lesion detection justifying the extended scan duration for surveillance of patients with cancer predisposition disorders. Although it may be uncommon to find lesions exclusively on DWI, the relevance of early cancer diagnosis justifies the time and resources invested in performing this sequence. Table of contents/Outline: 1. WB-MRI protocols for cancer surveillance in pediatric patients with cancer predisposition disorders. 2. Presentation of cases of: - Discordant results between DWI and STIR/T2 MRI sequences, false-negative results on STIR/T2 solely. - Concordant results between DWI and STIR/T2 MRI sequences, true-positive results. 3. Examples of artifacts in DW-MRI that may preclude an accurate diagnosis and approaches to avoid or to minimize them. Read More
Meeting name: SPR 2025 Annual Meeting , 2025
Authors: Reyes Recasens Magdalena, Arenos-abril Jesus, Doria Andrea
Keywords: Whole Body MRI, Cancer, Surveillance Imaging
Cavernous transformation of the portal vein (CTPV) is characterized by the formation of venous channels within and around a previously stenosed or occluded portal vein, serving as portoportal collateral vessels. It is a major cause of portal hypertension in children and requires a multifaceted management approach, including medical therapy, interventional procedures such as portal recanalization, and surgical treatments ranging from shunt creation to liver transplantation in end-stage cases. CT-angiography, in combination with portal venography, is the key imaging modality for determining the optimal treatment strategy. It is essential not only for assessing liver cirrhosis and secondary signs of portal hypertension—such as portosystemic collaterals, splenomegaly, and ascites—but also for providing detailed anatomical mapping critical for surgical planning. This presentation will illustrate various pediatric cases of CTPV and discuss the optimal management approach based on factors including the presence or absence of liver cirrhosis, dominant portal collaterals, intrahepatic portal flow, proper superior mesenteric vein communicating with the porta hepatis, and splenorenal shunts, among others. For each scenario a therapeutic plan will be suggested based upon clinical and imaging criteria. By the end of this presentation, readers will be able to: Optimize CT protocols for evaluating CTPV; enhance reporting using a structured checklist of key findings; and support clinical decision-making in collaboration with multidisciplinary teams. Read More
Meeting name: IPR 2026 Congress , 2026
Authors: Arenos-abril Jesus, Moreira Maricela, Barnes Navarro Daniel, Padros Fornieles Cristina, Molino Gahete Jose Andres, Riaza Lucía
Keywords: Liver, Portal Vein Thrombosis, Portal Hypertension