Placental insufficiency represents a major challenge in obstetrics, leading to FGR, preeclampsia, and stillbirth. Diagnosis is often delayed until significant fetal compromise has occurred, highlighting an urgent need to develop non-invasive tools for earlier detection. The guinea pig is an ideal translational model, sharing human-like hemomonochorial placentation, but longitudinal assessment remains challenging. We have previously demonstrated the feasibility of terminal CEUS to assess maternal and fetal placental circulation, a critical gap remains in tracking placental changes throughout gestation. The goal of this study was to establish and demonstrate the feasibility of a reproducible protocol for longitudinal multimodal US to characterize the normal temporal evolution of the placenta and its vasculature in a control cohort. This work focuses on acquiring B-mode, Color/Power Doppler, Spectral Doppler, and SWE data across gestation. Read More

Meeting name: IPR 2026 Congress , 2026

Authors: Haddad Sophie, Curtin Kathrine, Davis Laura, Lee Daeyeon, Hwang Misun

Keywords: Placenta, Ultrasound

Infantile myofibromatosis is rare. The generalized form affects the integument and musculoskeletal system as well as multiple visceral organs and can impair organ function, thus requiring prompt diagnosis and treatment at an early age. As a disease that presents before the age of two years, minimizing use of CT and MRI is imperative to reduce radiation and gadolinium contrast use, respectively. We present a case of a neonate in whom multiple cutaneous and an appendiceal lesion raised the suspicion of infantile myofibromatosis. Multiple liver lesions were seen on gray-scale ultrasound. On contrast-enhanced ultrasound (CEUS), there were multiple, differently-enhancing liver lesions, a finding which was confirmed on MRI with hepatocyte specific contrast. These were all thought to represent myofibromas with complete involution following low dose chemotherapy. Read More

Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024

Authors: Davis Laura, Morales-tisnés Tatiana, Lerebo Wondwossen, Barz Leahy Allison, Ntoulia Aikaterini, Dennis Rebecca, Anupindi Sudha, Darge Kassa, Back Susan

Keywords: myofibromatosis, contrast ultrasound, CEUS