Showing 5 Abstracts.
The indications for high resolution CT (HRCT) and bronchoscopy often coincide in patients with recurrent respiratory tract infections, chronic cough and wheezing, symptoms often related to tracheomalacia (TM). However, the efficacy for detecting TM in young children by HRCT has not been investigated. The aim of this investigation is to evaluate the ability to detect TM on clinical HRCT relative to bronchoscopy as a reference standard and compare several quantitative methods of determining the presence of TM on CT. Read More
Meeting name: SPR 2017 Annual Meeting & Categorical Course , 2017
Authors: Xia Christina, Das Prasnjeet, Thomen Robert, Woods Jason, Fleck Robert
Keywords: Tracheomalacia, Bronchoscopy, Computed Tomography
CT is often performed and advocated in patients with risk factors for or symptoms of tracheomalacia (TM). However, TM is traditionally defined as a 50% decrease in the cross-sectional area of the airway during a forced expiratory maneuver. This basis for detecting TBM was never meant for use in CT and leads to the under diagnosis of TM in young children by CT and typically requires inspiratory/expiratory CT (IECT). Additionally, some pictures archiving systems do not have tools to measure area. The aim of this investigation is to show that TM is under diagnosed by IECT relative to bronchoscopy and to develop a “view box” parameter to improve sensitivity while maintaining specificity in identifying the trachea as normal or affected by TM. Read More
Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016
Authors: Das Prasnjeet, Thomen Robert, Halula Sarah, Woods Jason, Fleck Robert
Keywords: Bronchoscopy, trachea, bronchomalacia, airway, dynamic CT
To develop an optimized AI model to automatically segment lung volumes from pulmonary magnetic resonance images (MRI) and generate tidal volume calculations for neonatal patients with chronic lung disease of prematurity (bronchopulmonary dysplasia, BPD). Read More
Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024
Authors: Mahalingam Neeraja, Bates Alister, Higano Nara, Gunatilaka Chamindu, Woods Jason, Somasundaram Elanchezhian
Keywords: Bronchopulmonary Dysplasia, MRI, Deep Learning
BPD is associated with pulmonary hypertension (PH) and patients with BPD-associated PH (BPD-PH) have increased morbidity and mortality. Noninvasive assessment of BPD-PH has traditionally relied on echocardiograms. However, recent advances have allowed the use of MRI in the assessment of respiratory and cardiac disease in infants with BPD. In adults and older pediatric patients, increased left ventricular eccentricity index (MR-EI) and decreased MRI septal curvature correlate with increased mean pulmonary artery pressure and pulmonary vascular resistance. The current study sought to determine the relationship of MR-EI and septal curvature in neonates with BPD and BPD-PH with short term respiratory outcomes and need for pulmonary vasodilator therapies. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Critser Paul, Higano Nara, Kingma Paul, Fleck Robert, Lang Sean, Hirsch Russel, Taylor Michael, Woods Jason
Tracheomalacia (TM) is a common morbidity associated with prematurity and manifests as dynamic collapse of the trachea lumen due to cyclic changes of intrathoracic pressure during breathing. Premature infants often have elevated work of breathing (WOB) related to their distal, small airway and lung abnormalities. The large airway contribution to WOB can be determined using computational fluid dynamics (CFD), which is a well-known technique to calculate the resistance and WOB in the human airway. However, previous studies are based on static airway geometry without motion. Using the novel technique of ultrashort echo time (UTE) magnetic resonance imaging (MRI), the tidal volume and airway motion can be used to create a dynamic model for use in CFD. Our aim is to calculate the estimated WOB in a dynamic trachea with neonatal TM compared with a stable, static trachea. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Gunatilaka Chamindu, Bates Alister, Higano Nara, Hahn Andrew, Fain Sean, Hysinger Erik, Fleck Robert, Woods Jason
Keywords: Bronchopulmonary Dysplasia, MRI, Prematurity