Showing 2 Abstracts.
ARPKD causes diffuse microcysts in the kidney parenchyma, and cyst burden cannot be quantified by standard image segmentation methods. We sought to assess whether apparent diffusion coefficient (ADC) measured by DWI could serve as a non-invasive biomarker of ARPKD severity, with the hypothesis that ADC would be higher in cystic vs. non-cystic parenchyma due to higher extracellular water content. We examined whether ADC could distinguish healthy kidneys from those affected by ARPKD, and whether a threshold ADC value could be established to differentiate cystic vs. non-cystic parenchyma. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Heintzelman Briana, Khrichenko Dmitry, Carson Robert, Darge Kassa, Serai Suraj, Hartung Erum
ARPKD causes diffuse microcysts in the kidney parenchyma, and cyst burden cannot be quantified by standard image segmentation methods. We sought to assess whether apparent diffusion coefficient (ADC) measured by DWI could serve as a non-invasive biomarker of ARPKD severity, with the hypothesis that ADC would be higher in cystic vs. non-cystic parenchyma due to higher extracellular water content. We examined whether ADC could distinguish healthy kidneys from those affected by ARPKD, and whether a threshold ADC value could be established to differentiate cystic vs. non-cystic parenchyma. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Heintzelman Briana, Khrichenko Dmitry, Carson Robert, Darge Kassa, Serai Suraj, Hartung Erum