Showing 5 Abstracts.
Review the set up for a pediatric MRU exam. I will identify what needs to be done to aquire optimal images and functional information. I will also highlight challenges and pitt falls of the exam. Read More
Meeting name: SPR 2018 Annual Meeting & Postgraduate Course , 2018
Authors: Carson Robert
Keywords: MR Urogram, MRI Urogram, MRU
ARPKD causes diffuse microcysts in the kidney parenchyma, and cyst burden cannot be quantified by standard image segmentation methods. We sought to assess whether apparent diffusion coefficient (ADC) measured by DWI could serve as a non-invasive biomarker of ARPKD severity, with the hypothesis that ADC would be higher in cystic vs. non-cystic parenchyma due to higher extracellular water content. We examined whether ADC could distinguish healthy kidneys from those affected by ARPKD, and whether a threshold ADC value could be established to differentiate cystic vs. non-cystic parenchyma. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Heintzelman Briana, Khrichenko Dmitry, Carson Robert, Darge Kassa, Serai Suraj, Hartung Erum
ARPKD causes diffuse microcysts in the kidney parenchyma, and cyst burden cannot be quantified by standard image segmentation methods. We sought to assess whether apparent diffusion coefficient (ADC) measured by DWI could serve as a non-invasive biomarker of ARPKD severity, with the hypothesis that ADC would be higher in cystic vs. non-cystic parenchyma due to higher extracellular water content. We examined whether ADC could distinguish healthy kidneys from those affected by ARPKD, and whether a threshold ADC value could be established to differentiate cystic vs. non-cystic parenchyma. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Heintzelman Briana, Khrichenko Dmitry, Carson Robert, Darge Kassa, Serai Suraj, Hartung Erum
Ultra-Short Echo Time (UTE) imaging, characterized by acquisition schemes with Echo Times (TE) of < 1 msec, have enabled new applications of pediatric musculoskeletal (MSK) MRI including cortical bone, tendons and ligaments. The protons in the bone collagen matrix have an effective T2* on the order of 20 – 80 µsec. The UTE sequence consists of a 40 µs long non-selective RF pulse followed by transmit/receive switch time and a 100% asymmetric data, i.e. free induction decay, acquisition from the center to the surface of a sphere. In order to achieve the shortest possible TE, data acquisition starts already during ramp-up time of the readout gradient. The aim of our study was to assess the feasibility and compare two UTE sequences, a prototype 3D UTE with radial koosh-ball acquisition and clinically available pointwise encoding time reduction with radial acquisition (PETRA), in pediatric patients referred for clinical MSK studies. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Serai Suraj, Carson Robert, Venkatesh Tanvi, Kollasch Peter, Liu Ke Cheng, Rajapakse Chamith, Nguyen Jie
Keywords: UTE
Anatomic changes during bone growth and skeletal maturation are under-studied and incompletely understood, partially attributed to the sparing use of ionizing radiation in children. Recently, a clinically-feasible UTE (ultra-short echo time) MRI technique has emerged, enabling the direct visualization of bone. Although validated in adults, its spatial resolution and reproducibility have not been fully investigated in children. Therefore, the purpose of this study is 1) to determine the feasibility of UTE MRI to quantify changes in vertebral porosity and disc hydration along the thoracolumbar spine and 2) to investigate inter-rater reproducibility. Read More
Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020
Authors: Nguyen Jie, Hong Shijie, Nguyen Michael, Venkatesh Tanvi, Serai Suraj, Carson Robert, Barrera Christian, Cahill Patrick, Rajapakse Chamith
Keywords: quantitative MRI, bone, spine