This electronic educational poster will first introduce the concept behind Compressed Sensing - a very powerful MR technique (that has just become commercially available in 2018) allowing for, amongst many different applications, acceleration of MR data acquisition beyond parallel imaging (SENSE, GRAPPA, ASSET). Then, the poster will show comparative clinical examples of application of Compressed Sensing onto commonly used cardiovascular MR sequences such as 1) cine balanced SSFP, both breath-hold and non-breath-hold examinations, 2) cine phase contrast in free-breathing, and 3) respiratory-navigated 3D Whole-Heart examination using T1-weighted fast gradient echo sequence with DIXON technique. In these clinical examples, Compressed Sensing, in addition to parallel imaging, can further accelerate the acquisition time to allow for less number of breath-holds for patients to complete a stack of cine images through the ventricles without sacrificing spatial or temporal resolution or signal-to-noise ratio. The acquisition time of free-breathing cine phase contrast can be reduced and yield accurate flow quantification. The increased speed of acquisition can be traded off to achieve higher spatial resolution in young patients who may not be able to achieve long breath-hold times otherwise needed when high spatial resolution is necessary. These clinical examples were accumulated since January 2017 with a Compressed Sensing software patch made available by the scientific research group of the MR vendor under research agreement and the clinical use was approved by Institutional Review Board. Read More

Meeting name: SPR 2019 Annual Meeting & Postgraduate Course , 2019

Authors: Chung Taylor, Doneva Mariya, Lu Quin, Hitt Dave, Tamir Jonathan

Keywords: Magnetic Resonance

4D flow MRI with full coverage of the heart and proximal vessels is a powerful tool to understand hemodynamic pathology arising from congenital heart disease (CHD) and subsequent surgery; however, scan times often exceed 10 minutes thereby limiting widespread adoption in pediatrics. Decreasing scan time using compressed-SENSE (CS), a combination of conventional parallel imaging (SENSE) and randomized spatial undersampling, shows promise over SENSE alone. However, both the feasibility and its effect on accurate flow quantification in pediatrics has not been evaluated. This study investigated the feasibility of CS for pediatric 4D flow MRI to quantify flow indices used in risk stratification of CHD such as coarctation or pulmonary regurgitation, in comparison with SENSE. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Fujiwara Takashi, Browne Lorna, Malone Ladonna, Lu Quin, Fonseca Brian, Dimaria Michael, Barker Alex

Keywords: 4D flow, Compressed SENSE, Congenital heart disease

Current musculoskeletal MR imagiing utilizes multiple imaging planes and multiple weightings of two-dimensional turbo spin echo (2D TSE) to precisely delineate and characterize intra-articular abnormalities. Three-dimensional (3D) TSE sequences are currently available on most MRI vendor platforms. High resolution isotropic 3D imaging of the small joints reduces partial volume artifacts and allows for the reconstruction in any orientation, thus eliminating the need to acquire additional scans of different orientations with identical tissue contrast. However, the typical trade off of achieving very high resolution (under 0.5mm isotropic) is long acquisition time. Scan time reduction can be achieved with parallel imaging at the expense of reducing the signal-to-noise ratio (SNR) and with increasing the echo train length at the expense of image blurring. The addition of compressed sensing (CS), a recently commercially available acceleration technique, allows for decrease in acquisition time without the significant loss of SNR experienced with identical acceleration factors achieved with parallel imaging alone. CS exploits (1) image data sparsity via application of a sparsity transform of the image data; (2) pseudo-random-type of k-space sampling; (3) non-linear iterative reconstruction. We utilized CS to decrease scan time (range 4:55 to 5:35 minutes) of 3D PD FS TSE sequences to obtain high resolution (voxel size 0.45 x 0.45 x 0.45) imaging of the fingers, toes, wrist and feet. In this educational exhibit, we will review the normal anatomy and pathology of small joints Read More

Meeting name: SPR 2019 Annual Meeting & Postgraduate Course , 2019

Authors: Padua Eric, Kammen Bamidele, Karakas S Pinar, Hitt Dave, Tai Chau, Pandya Nirav, Lu Quin, Chung Taylor

Keywords: musculoskeletal

<b>Introduction</b>: Conventional pediatric MRI acquisitions of a short axis (SA) stack for ventricular volumes typically requires one breath-hold per slice, resulting in multiple coordinated breath-holds under anesthesia to acquire the entire stack. Here, we aim to validate a compressed sensing approach to reduce breath-holding during SA balanced steady state free precession (bSSFP) cine imaging. Equivalency is tested via qualitative image scoring and global volumes compared to conventional bSSFP cine imaging. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Naresh Nivedita, Browne Lorna, Barker Alex, Malone Ladonna, Fujiwara Takashi, Hulseberg-dwyer Emma, Mcgee Janet, Lu Quin, Twite Mark, Dimaria Michael, Fonseca Brian

Keywords: Compressed Sensing, Cardiac Function, Anesthesia