Rozenfeld Michael,  Garcia Sebastian,  Nelson Paige,  Burrowes Delilah

Final Pr. ID: Poster #: EDU-070

Gadolinium based contrast agents (GBCAs) are widely used in medical imaging with 10 million annual doses given in the US alone. There is a very low 0.03% risk of serious adverse reactions. GBCAs were thought entirely safe until 2006 when reports of nephrogenic system fibrosis (NSF) surfaced. NSF was nearly eliminated by 2009 through careful screening and reducing dosage. In 2014, it was reported that GBCAs may deposit in the brains of patients. The purpose of this review is to examine the literature to date. Read More

Authors:  Rozenfeld Michael , Garcia Sebastian , Nelson Paige , Burrowes Delilah

Keywords:  Brain, Gadolinium

Bhatia Aashim,  Khrichenko Dmitry,  Otero Hansel

Final Pr. ID: Paper #: 002

This study will normalize contrast enhancement curves for three GBCAs in fMRU and use it to assess for differences in renal enhancement characteristics of different GBCAs used in pediatric fMRU. Read More

Authors:  Bhatia Aashim , Khrichenko Dmitry , Otero Hansel

Keywords:  Functional, Gadolinium, Urography

Albers Brittany,  Shah Chetan

Final Pr. ID: Poster #: EDU-081

Gadolinium based contrast agents have been used in pediatric neuroradiology for years and are thought to be safe when administered appropriately. However, it has been discovered that gadolinium used in routine clinical practice results in gadolinium deposition in the even in patients with normal renal function. No studies have addressed gadolinium deposition in the soft tissues of pediatric patients or its potential ill-effects. The potential for harm may exist. We reviewed our gadolinium use in the follow up of pediatric primary intracranial neoplasms. Read More

Authors:  Albers Brittany , Shah Chetan

Keywords:  contrast, safety, malignancy, gadolinium, follow-up

Stanescu Arta,  Maloney Ezekiel,  Shaw Dennis

Final Pr. ID: Paper #: 085

The long term effects of retained Gadolinium (Gd) are still under investigation, but may be of greater concern in pediatric patients.
So far several factors that appear to influence Gd retention have been described. The chemical structure of the Gadolinium based contrast agents (GBCA) plays an important role, with linear agents showing greater deposition compared with macrocyclics, attributed to lower chelate affinity. Differences in GBCA washout may also play a role.
In this study we investigated and quantified the presence of Gd bone deposits in pediatric patients receiving GBCA as well as in controls with no known exposure. Read More

Authors:  Stanescu Arta , Maloney Ezekiel , Shaw Dennis

Keywords:  Gadolinium, Deposition, bone

Lam Christopher,  Chavhan Govind

Final Pr. ID: Poster #: EDU-019

Gadolinium-based contrast agents (GBCAs) are widely used in clinical practice. However, there are growing concerns regarding the safety of GBCAs with recent findings of gadolinium deposition in patients with normal renal function. This educational exhibit reviews the use of gadolinium in children, including the safety profile, existing controversies, and potential solutions. Read More

Authors:  Lam Christopher , Chavhan Govind

Keywords:  nephrogenic systemic fibrosis, gadolinium deposition disease, gadolinium toxicity

Zucker Evan

Final Pr. ID: Poster #: EDU-093

Cardiomyopathy is rare in children but associated with significant morbidity and mortality when symptomatic. It also comprises a large proportion of cardiac MR imaging referrals in typical pediatric radiology practice. The purpose of this educational exhibit is to review the major types of cardiomyopathy in children, focusing on cardiac MRI. Read More

Authors:  Zucker Evan

Keywords:  Cardiomyopathy, Cardiac, MRI, Pediatric, Late gadolinium enhancement