Akbari Yasmin,  Kralik Stephen

Final Pr. ID: Paper #: 159

Cervical spine trauma, particularly at the craniocervical junction, can produce significant morbidity and mortality in the pediatric population. Although normative pediatric cervical spine CT measurements have been reported, the accuracy of these measurements for predicting ligamentous injury remains unknown. The purpose of this study is to evaluate the sensitivity and specificity of normative pediatric CT measurements for prediction of traumatic ligamentous injury at the craniocervical junction, using MRI as gold standard. Read More

Authors:  Akbari Yasmin,  Kralik Stephen

Keywords:  Cervical spine ,  Trauma ,  CT

Goncalves Fabricio,  Khrichenko Dmitry,  Martin-saavedra Juan,  Alves Cesar Augusto,  Teixeira Sara,  Andronikou Savvas,  Vossough Arastoo

Final Pr. ID: Paper #: 160

Accurate preoperative imaging diagnosis of supratentorial pediatric intraventricular tumors is not always straightforward. Conventional MRI features such as T1- and T2-weighted signal and contrast enhancement may overlap among various choroid plexus tumors and embryonal tumors. This study aimed to perform apparent diffusion coefficient (ADC) histogram analysis, assessing various metrics in different intraventricular for histological classification. Read More

Authors:  Goncalves Fabricio,  Khrichenko Dmitry,  Martin-saavedra Juan,  Alves Cesar Augusto,  Teixeira Sara,  Andronikou Savvas,  Vossough Arastoo

Keywords:  Intranventricular tumors ,  ADC ,  Diffusion

Goncalves Fabricio,  Khrichenko Dmitry,  Zheng Qiang,  Hwang Misun

Final Pr. ID: Paper #: 161

Ultrasound (US) is a powerful imaging tool in the evaluation of neonates with suspected hypoxic-ischemic encephalopathy (HIE). US evaluation of the neonatal brain has been mainly performed qualitatively, comparing intracranial structures with different echotextures. Qualitative US analysis of the neonatal HIE brain may vary according to technical variations, the severity of the injury and the presence of coexistent complications. Quantitative analysis of the neonatal brain echotexture has been seldom attempted. Our aim was to compare the echotextures of specific brain regions between HIE patients and controls. Read More

Authors:  Goncalves Fabricio,  Khrichenko Dmitry,  Zheng Qiang,  Hwang Misun

Keywords:  Ultrasound ,  Hypoxic-ischemic encephalopathy

Goncalves Fabricio,  Wang Dah-jyuu,  Goldman-yassen Adam,  Martin-saavedra Juan,  Alves Cesar Augusto,  Teixeira Sara,  Andronikou Savvas,  Vossough Arastoo

Final Pr. ID: Paper #: 162

Proton MRS (1H-MRS) is a technique to non-invasively study brain metabolites in vivo. 1H-MRS has been shown to detect abnormal brain accumulation of lactate in primary mitochondrial disorders (PMDs). However, differences in lactate concentration among the different PMDs have not been explored. We aimed to explore differences in quantitative 1H-MRS derived metabolite concentrations, particularly of lactate, and their ratios, in PMDs. We analyzed quantitative 1H-MRS data of the brain in pediatric patients with different types of genetically confirmed PMDs to evaluate differences in metabolite concentration and ratios. Read More

Authors:  Goncalves Fabricio,  Wang Dah-jyuu,  Goldman-yassen Adam,  Martin-saavedra Juan,  Alves Cesar Augusto,  Teixeira Sara,  Andronikou Savvas,  Vossough Arastoo

Keywords:  MR Spectroscopy ,  Mitochondrial ,  LCModel

Fetzer Daniel,  Aaen Gregory,  Udochukwu Oyoyo,  Achiriloaie Adina

Final Pr. ID: Paper #: 164

Pediatric multiple sclerosis (MS) is difficult to diagnose at presentation, and the clinical features often overlap those of acute disseminated encephalomyelitis (ADEM), neuromyelitis optica or clinically isolated syndrome. Established criteria for diagnosing MS are less reliable in pre-pubescent children. We seek to qualitatively and quantitatively define the MRI features of pediatric MS compared to ADEM at initial presentation. Read More

Authors:  Fetzer Daniel,  Aaen Gregory,  Udochukwu Oyoyo,  Achiriloaie Adina

Keywords:  Multiple sclerosis ,  ADEM ,  white matter disease

Arceo Salvador,  Christopher Ross,  Milla Sarah,  Riedesel Erica

Final Pr. ID: Paper #: 165

Head trauma is a significant cause of morbidity and mortality in pediatrics. Non-contrast Head CT is the accepted gold standard imaging study to evaluate for suspected acute intracranial hemorrhage (ICH), however small acute extra-axial hemorrhage may be easily missed due to size and similar density to the bony calvarium. In Dual Energy CT (DECT), materials within the body such as bone/calcium and hemorrhage can be more easily discriminated based on differential attenuation at high and low peak voltage image acquisitions. This allows for advanced post-processing including automated bone removal which has been shown to improved visualization of acute ICH in the adult radiology literature, but has not yet been described in pediatrics. We report a retrospective review of DECT with automated bone removal for detection of acute ICH in the pediatric population. Read More

Authors:  Arceo Salvador,  Christopher Ross,  Milla Sarah,  Riedesel Erica

Keywords:  Dual Energy ,  Trauma ,  Intracranial Hemorrhage

Radhakrishnan Shilpa

Final Pr. ID: Paper #: 166

Isolated developmental delay (IDD) is commonly encountered in daily practice and the cause is frequently unknown. Conventional MR Imaging usually fails to reveal an abnormality.MR Spectroscopy (MRS) can assess variations in metabolite ratios and correlate this with abnormalities in brain structure such as disorders of myelination. However, the normal ranges of these metabolites is not well established in children and vary by age. We sought to use the data from multivoxel 3T MRS to characterize the metabolite ratios in different parts of the brain as a function of age in children with IDD vs age-matched controls. Read More

Authors:  Radhakrishnan Shilpa

Keywords:  M R Spectroscopy ,  developmental delay

Alves Cesar Augusto,  Teixeira Sara,  Martin-saavedra Juan,  Goncalves Fabricio,  Goldstein Amy,  Andronikou Savvas,  Ganetzky Rebecca,  Vossough Arastoo

Final Pr. ID: Paper #: 167

Primary mitochondrial disorders (PMD) in newborns can be misdiagnosed as hypoxic-ischemic encephalopathy (HIE), clinically and radiologically. The purpose of this study is to describe the frequency and patterns of brain MRI findings in children with PMD diagnosed during the neonatal period. Read More

Authors:  Alves Cesar Augusto,  Teixeira Sara,  Martin-saavedra Juan,  Goncalves Fabricio,  Goldstein Amy,  Andronikou Savvas,  Ganetzky Rebecca,  Vossough Arastoo

Keywords:  Newborn ,  mitochondrial disorders ,  Mitochondrial